Born 8 Dec. 1833 at Preston, Lancashire, England.1 Daughter of Henry Nightingale and Agnes Leach.2 Emigrated from Liverpool with her family aboard the Sheffield, arriving in New Orleans 31 Mar. 1841.3 Moved to St. Louis, by 31 Jan. 1847.4 Married John T. Caine, 22 Oct. 1850, at St. Louis; thirteen children.5 Represented Utah Territory in Washington DC at meetings of the National Woman Suffrage Association, beginning 1882.6 Lived in Washington DC while her husband served in the U.S. Congress as a representative for Utah Territory, 1883–1893.7 Spoke on the Utah silk industry at the Columbian Exposition at the World’s Fair in Chicago, June 1893.8 Directed the Utah woman’s department exhibit at the California Midwinter International Exposition in San Francisco, 1894.9 Spoke at the semiannual meeting of the Utah Woman’s Silk Association, 22 Jan. 1895, regarding the exhibit at the Midwinter Fair in 1894.10 Appointed as secretary and treasurer of the Silk Association, Apr. 1896.11 Presented a paper on sericulture at the International Council of Women conference in London, June–July 1899.12 Served as secretary of the Utah Silk Commission, 1899–1900.13 Member of the Relief Society general board, 1902–1907.14 Died 17 July 1911 at Salt Lake City.15